منابع مشابه
Promoter reuse in prokaryotes
Anecdotal evidence shows promoters being reused separate from their downstream gene, thus providing a mechanism for the efficient and rapid rewiring of a gene's transcriptional regulation. We have identified over 4000 groups of highly similar promoters using a conservative sequence similarity search in all fully sequenced prokaryotic genomes. About 6% of those groups are shared between bacteria...
متن کاملPromoter propagation in prokaryotes
Transcriptional activation or 'rewiring' of silent genes is an important, yet poorly understood, phenomenon in prokaryotic genomes. Anecdotal evidence coming from experimental evolution studies in bacterial systems has shown the promptness of adaptation upon appropriate selective pressure. In many cases, a partial or complete promoter is mobilized to silent genes from elsewhere in the genome. W...
متن کاملSuperhelically Destabilized Sites in the E. coli Genome: Implications for Promoter Prediction in Prokaryotes
Stress-induced DNA duplex destabilization (SIDD) analysis exploits the known structural and energetic properties of DNA to predict which sites become susceptible to strand separation under superhelical stress. Experimental results show that this analysis is quantitatively accurate in predicting destabilized sites that occur in transcriptional regulatory regions, matrix/scaffold attachment sites...
متن کاملMetal inducible activity of the oil palm metallothionein-like gene promoter (MT3-A) in prokaryotes.
Reporter gene activity under the regulation of the oil palm metallothionein-like gene, MT3-A promoter was assessed in prokaryotes. Vector constructs containing MT3-A promoter with (W1MT3-A) and without (W2MT3-A) five prime untranslated region (5'-UTR) fused to ß-glucuronidase (GUS) gene in pCAMBIA 1304 vector were produced. 5'-rapid amplification of cDNA ends (RACE) using mRNA isolated from Esc...
متن کاملInvestigating Embedded Question Reuse in Question Answering
The investigation presented in this paper is a novel method in question answering (QA) that enables a QA system to gain performance through reuse of information in the answer to one question to answer another related question. Our analysis shows that a pair of question in a general open domain QA can have embedding relation through their mentions of noun phrase expressions. We present methods f...
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ژورنال
عنوان ژورنال: Mobile Genetic Elements
سال: 2012
ISSN: 2159-256X
DOI: 10.4161/mge.23195